Shandong Aure Chemical Co., Ltd.

4-(3-Chloropropyl)morpholine CAS 7357-67-7

Persistent supply for specialized needs
4-(3-Chloropropyl)morpholine CAS 7357-67-7
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4-(3-Chloropropyl)morpholine CAS 7357-67-7

Synonyms: 3-Morpholinopropyl chloride; N-(3-Chloropropyl)morpholine; 4-(3-Chloropropyl)morpholine; Morpholine, 4-(3-chloropropyl)-; 1-Chloro-3-morpholinopropane; 3-Chloro-1-(morpholin-4-yl)propane; 3-(Morpholin-4-yl)propyl chloride

Shandong Aure Chemical Co., Ltd. is one of the leading suppliers of 4-(3-Chloropropyl)morpholine in China.

We can provide customized requirements in terms of product purity, packaging specifications, and other aspects.

Please contact us to obtain the latest product information.

Product Details

Aure Chemical: Trusted Source of 4-(3-Chloropropyl)morpholine CAS 7357-67-7

4-(3-Chloropropyl)morpholine is a chloroalkyl-substituted morpholine derivative that functions as a versatile alkylating agent in organic synthesis. The terminal chlorine provides a reactive site for nucleophilic substitution, enabling attachment of the morpholinopropyl moiety to various substrates.

It is particularly valued as an intermediate in the synthesis of pharmaceutical compounds. Aure Chemical offers consistent quality material suitable for fine chemical production and research applications.


Basic Information

CAS No.7357-67-7
EC No.461-510-0
Linear FormulaC7H14ClNO
Molecular Weight163.65
AppearanceColorless to light yellow liquid
Melting PointNot available (typical reference)
Boiling point115 °C at 25 mmHg (lit.)
Density1.04 g/cm³ (lit.)
SolubilitySoluble in common organic solvents
Storage ConditionsKeep in a cool, dry place, sealed tightly, protected from moisture
Chemical StructureMolecular Structure of 4-(3-Chloropropyl)morpholine

Key Applications

  • Pharmaceutical intermediate: Used as a key building block in the synthesis of tyrosine kinase inhibitors such as gefitinib and related anticancer agents.

  • Organic synthesis intermediate: Serves as an alkylating reagent for introducing the morpholinopropyl group into target molecules.

  • Fine chemical intermediate: Applied in the preparation of specialty nitrogen-containing compounds for pharmaceutical and agrochemical research.

  • Process development: Supports route optimization and scale-up for multi-step pharmaceutical manufacturing processes.

  • Custom synthesis: Enables flexible incorporation of functional side chains in custom medicinal chemistry projects.


Aure Chemical: Your Reliable Partner

  • Consistent product quality: Aure Chemical provides material with controlled purity and reliable batch consistency suitable for pharmaceutical intermediate applications.

  • Flexible global supply: We offer stable international logistics and supply support for laboratory, pilot, and production-scale quantities.

  • SDS and COA support: Safety data sheets and certificates of analysis are available upon request to meet quality and regulatory requirements.

  • Packaging and technical service: Customized packaging in 1 kg to 25 kg sizes with inner liners, backed by responsive technical communication.

Packaging, Logistics & Compliance Capabilities

Aure Chemical provides flexible packaging solutions, compliant logistics arrangements, and controlled storage practices to support laboratory-scale, pilot-scale, and commercial-scale global supply.

Packaging Options

  • 25 kg / 50 kg bags (fiber drum, aluminum bag, HDPE drum)
  • 100 kg / 200 kg steel or HDPE drums
  • 500 kg / 1000 kg IBC containers
  • Bulk liquids in ISO tank containers
  • Customized packaging upon request

Transportation Modes

  • Sea freight (FCL / LCL)
  • Air freight for selected products
  • Road and rail transportation
  • Dangerous & non-dangerous cargo handling
  • Incoterms: EXW, FOB, CFR, CIF, DAP, DDP

Storage & Handling

  • Dry, cool, and well-ventilated warehouses
  • Segregation by hazard class
  • FIFO inventory management
  • Temperature-controlled storage if required
  • Regular inspection & labeling control

Documentation & Compliance

  • Safety Data Sheet (SDS)
  • Certificate of Analysis (COA)
  • Dangerous Goods Declaration (DGD)
  • Packing List & Commercial Invoice
  • IMDG / IATA / ADR compliant labeling

For packaging customization or logistics consultation, please contact us.


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