4-Chlorophenol CAS 106-48-9

4-Chlorophenol (p-Chlorophenol) Product Overview

4-Chlorophenol (CAS 106-48-9), commonly known as p-Chlorophenol or para-Chlorophenol, is one of the three positional isomers of monochlorophenol. In this molecule, the chlorine substituent is located at the para position relative to the phenolic hydroxyl group.

With a melting point around 42–45°C, 4-Chlorophenol is normally handled as a crystalline solid at ambient temperature but can be maintained in molten form under controlled heating. It is used primarily as an intermediate and aromatic building block in organic synthesis.

Basic Information of 4-Chlorophenol

4-Chlorophenol (CAS 106-48-9), also known as p-Chlorophenol or para-Chlorophenol, is the para-substituted isomer of monochlorophenol. It has the molecular formula C6H5ClO and a molecular weight of 128.55 g/mol. At normal ambient temperature, 4-Chlorophenol is generally a crystalline solid and becomes molten when heated above its melting range of approximately 42–45°C.

It is primarily used as an aromatic intermediate in organic synthesis, including the preparation of pharmaceutical, agrochemical, dye, pigment and other specialty chemical intermediates.

CAS No.:	106-48-9
EC No.:	203-402-6
Linear Formula:	Cl–C₆H₄–OH
Molecular Weight:	128.56
Appearance:	White to off-white crystalline solid
Physical state:	Solid at room temperature; becomes molten above its melting range
Odor:	Phenolic, characteristic odor.
Melting point:	Approx. 42–45 °C
Boiling point:	220 °C (lit.)
Density:	1.306 g/mL at 25 °C (lit.)
Solubility:	Slightly soluble in water; readily soluble in ethanol, ether, chloroform, and other organic solvents.
Flash point:	240 °F
Nature:	Combustible, corrosive, harmful if swallowed or inhaled, toxic by skin absorption.
RIDADR:	UN 1992 3,8 /PG 1
Chemical Structure:

Our commitment to delivering high-purity 4-Chlorophenol ensures a reliable and efficient component for your complex manufacturing and synthesis processes.

Primary Applications of 4-Chlorophenol (p-Chlorophenol)

4-Chlorophenol's distinct chemical reactivity and biological activity make it an incredibly valuable and versatile intermediate with applications spanning numerous industries:

1. Pharmaceutical Synthesis:

   4-Chlorophenol is a crucial intermediate in the production of various active pharmaceutical ingredients (APIs). It's used in the synthesis of antiseptics, disinfectants, and other complex drug molecules, often serving as a precursor for more complex phenolic compounds.

2. Disinfectants and Antiseptics:

   Due to its potent antimicrobial properties, 4-Chlorophenol itself, or its derivatives, are used in certain disinfectant formulations for industrial, medical, and household applications. It's effective against a broad spectrum of microorganisms.

3. Agrochemical Manufacturing:

   It serves as a key building block in the synthesis of a variety of agrochemicals, including certain fungicides and herbicides, where the chlorinated aromatic structure imparts desired biological activity.

4. Dyes and Pigments:

   4-Chlorophenol is utilized as an intermediate in the production of specialty dyes and pigments, contributing to specific color properties and chemical stability.

5. Chemical Reagent & Specialty Chemicals:

   Beyond its major industrial uses, 4-Chlorophenol is also employed as a chemical reagent in various organic synthesis reactions, leading to a wide range of fine chemicals and specialized materials.

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Aure Chemical is dedicated to providing superior chemical solutions and unparalleled customer support. By partnering with us for your 4-Chlorophenol requirements, you benefit from:

• Exceptional Purity & Consistency: Our 4-Chlorophenol is manufactured to stringent purity specifications, crucial for maximizing yields in complex syntheses and ensuring consistent quality in your downstream products, especially for pharmaceutical and disinfectant applications.

• Reliable Global Supply Chain: We maintain a robust and efficient supply network, guaranteeing timely and secure delivery of this essential chemical to your facilities worldwide, adhering to all strict safety and regulatory standards for hazardous materials.

• Expert Technical Support: Our team of experienced chemists and specialists is readily available to offer comprehensive guidance on product application, safe handling procedures, and optimal storage conditions for 4-Chlorophenol.

• Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations, ensuring peace of mind for our clients handling this versatile material.

Choose Aure Chemical for a trustworthy and dependable supply of high-quality 4-Chlorophenol. We're ready to support your most demanding and innovative chemical manufacturing processes.

Hazards Classification

• GHS Classification: Flammable Liquid (GHS02), Corrosive (GHS05), Acute Toxicity (GHS06)

• Hazard Statements: Flammable liquid and vapor; causes severe skin burns and eye damage; toxic if inhaled; reacts violently with water releasing corrosive gases.

• UN Number: UN 2020

• Hazard Class: 6.1

• Handling Note:4-Chlorophenol is normally solid at ambient temperature because its melting point is approximately 42–45°C. For industrial processing requiring liquid transfer, controlled heating may be used to maintain the material in a molten state.

• Packing Group: I