Aromatic and Benzyl Amino Alcohols for Specialty Intermediates
Aromatic and benzyl amino alcohols are substituted amino alcohol intermediates that combine amine and hydroxyl functionality with phenyl, benzyl or substituted benzyl structural elements. These compounds may be used as building blocks in organic synthesis routes where aromatic substitution and amino alcohol functionality are required for further derivatization.
The combination of an amino alcohol structure with aromatic or benzyl substitution can influence polarity, steric effect, salt formation behavior and downstream reactivity. Depending on structure and specification, these intermediates may support alkylation, acylation, condensation, esterification, etherification or other controlled transformations.
This product group belongs to the broader family of amine derivatives for API synthesis and specialty chemical intermediates, alongside ethanolamine derivatives, tertiary amino alcohols, ether diamines, amino-PEG linkers and other specialty amine intermediates.
What Are Aromatic and Benzyl Amino Alcohols?
Aromatic amino alcohols are amino alcohol derivatives containing phenyl or substituted aromatic structures. In N-phenyl ethanolamine derivatives, the nitrogen atom is connected to a phenyl group while the molecule also contains hydroxyethyl functionality.
Benzyl amino alcohols contain benzyl or substituted benzyl groups attached to nitrogen or included in the side chain. N-benzyl ethanolamines, dibenzyl ethanolamines and fluorobenzyl amino alcohols are examples where benzyl substitution is combined with secondary or tertiary amino alcohol structure.
From a sourcing perspective, these products are usually evaluated by substitution pattern, assay, impurity profile, water content, color, appearance, odor, physical state, storage condition and documentation availability. The exact product choice depends on the target synthesis route and downstream process requirements.
Why These Intermediates Matter in Specialty Synthesis
Aromatic or benzyl substitution can provide structural diversity in intermediate design. The phenyl, benzyl or substituted benzyl group may influence reactivity, polarity, steric behavior or compatibility with subsequent synthesis steps, while the amino alcohol functionality provides additional sites for further derivatization.
These products may be used as substituted amino alcohol building blocks, specialty organic intermediates, fine chemical intermediates or API intermediate precursors depending on structure, specification and process requirements. Their role should be confirmed according to the actual application and customer specification.
In commercial sourcing, buyers usually review impurity profile, related aromatic impurities, residual solvents, water content, color, appearance, odor and batch-to-batch consistency. These factors may affect downstream reaction performance, purification, storage and customer acceptance.
Product Comparison Table
The following products represent selected aromatic amino alcohols, benzyl amino alcohols and substituted amino alcohol intermediates for specialty synthesis sourcing.
| Product | CAS No. | Structural Type | Typical Sourcing Focus | Product Page |
|---|---|---|---|---|
| N-Phenyldiethanolamine | 120-07-0 | N-phenyl diethanolamine derivative | Assay, water content, color, appearance, residual solvents | N-Phenyldiethanolamine CAS 120-07-0 |
| N-Methyl-N-phenylethanolamine | 93-90-3 | N-methyl-N-phenyl ethanolamine derivative | Assay, related aromatic impurities, water content, physical state | N-Methyl-N-phenylethanolamine CAS 93-90-3 |
| N-Benzylethanolamine | 104-63-2 | Secondary benzyl amino alcohol | Assay, benzyl-related impurities, color, odor, residual solvents | N-Benzylethanolamine CAS 104-63-2 |
| N,N-Dibenzylethanolamine | 101-06-4 | Tertiary dibenzyl amino alcohol | Assay, water content, appearance, related benzyl impurities | N,N-Dibenzylethanolamine CAS 101-06-4 |
| N-Benzyl-N-methylethanolamine | 101-98-4 | Tertiary benzyl methyl amino alcohol | Assay, related benzyl impurities, color, physical state | N-Benzyl-N-methylethanolamine CAS 101-98-4 |
| 3-Benzylamino-1-propanol | 4720-29-0 | Secondary benzylamino propanol | Assay, appearance, water content, residual solvents | 3-Benzylamino-1-propanol CAS 4720-29-0 |
| 2-(4-Fluorobenzylamino)ethanol | 22116-33-2 | Substituted fluorobenzyl amino alcohol | Assay, halogenated aromatic impurities, color, documentation | 2-(4-Fluorobenzylamino)ethanol CAS 22116-33-2 |
Key Product Groups
N-Phenyl Amino Alcohols
N-phenyl amino alcohols include N-phenyldiethanolamine and N-methyl-N-phenylethanolamine. These products contain phenyl-substituted nitrogen and hydroxyethyl functionality, making them relevant where N-phenyl amino alcohol structure is required in downstream synthesis.
Sourcing focus typically includes assay, water content, color, appearance, related aromatic impurities, residual solvents, physical state, packaging and documentation availability. For N-phenyl amino alcohol products, color and impurity profile may be important for downstream process acceptance.
N-Benzyl Ethanolamine Derivatives
N-benzyl ethanolamine derivatives include N-benzylethanolamine, N,N-dibenzylethanolamine and N-benzyl-N-methylethanolamine. These products contain benzyl substitution and hydroxyethyl functionality, with secondary or tertiary amine structures depending on substitution.
These intermediates may be evaluated where benzyl-substituted amino alcohol structure, salt formation behavior, hydroxyethyl functionality or further derivatization is required. Sourcing considerations include assay, related benzyl impurities, residual solvents, color, odor, water content, physical state, storage and packaging compatibility.
Benzylamino Propanol and Fluorobenzyl Amino Alcohols
3-Benzylamino-1-propanol and 2-(4-fluorobenzylamino)ethanol represent benzylamino propanol and substituted fluorobenzyl amino alcohol structures. These products may be evaluated where benzylamino structure, substituted aromatic group, amino alcohol functionality or side-chain construction is required.
For substituted aromatic amino alcohols, sourcing focus may include assay, appearance, related aromatic impurities, halogenated aromatic impurity profile where relevant, residual solvents, physical state, storage conditions and documentation availability.
Sourcing Considerations for Aromatic and Benzyl Amino Alcohols
Buyers sourcing aromatic and benzyl amino alcohols usually need to evaluate both technical specification and practical supply conditions. These products may differ in physical state, color tendency, odor, storage requirement and transport classification.
Purity and assay: Confirm the required assay level and analytical method according to downstream process needs.
Water content: Moisture may affect reaction performance, storage stability or customer acceptance.
Related amines: Related amino alcohol impurities should be reviewed according to product structure and specification.
Related aromatic impurities: Phenyl, benzyl or substituted aromatic impurities may be important for selected synthesis routes.
Residual solvents: Residual solvent control may be required for fine chemical and intermediate applications.
Color and appearance: Appearance requirements should be confirmed according to customer specification and intended use.
Odor: Some amine products may have characteristic odor, which can affect packaging and handling requirements.
Physical state: Confirm whether the material is liquid, solid, low-melting solid, viscous liquid or solution.
Melting range: Low-melting or temperature-sensitive behavior should be reviewed where applicable.
Storage conditions: Storage should be reviewed according to SDS, supplier recommendation and product stability.
Packaging compatibility: Packaging should match product properties, order quantity, moisture sensitivity and transport requirements.
Dangerous goods classification: Transport classification should be confirmed case by case according to the latest SDS and shipment route.
COA and SDS: COA and SDS may be available for confirmed products, subject to product and supplier confirmation.
Lead time: Availability may depend on production schedule, warehouse stock, batch release and inland transport.
Export documentation: Export documents, HS code reference and transport documents should be reviewed before shipment.
Small-batch packaging: Sample or small-batch packaging should be confirmed according to product properties and supplier arrangement.
Packaging and Logistics
Packaging for aromatic and benzyl amino alcohols should be selected according to physical state, odor, moisture sensitivity, hazard classification, supplier recommendation and order quantity. Liquid products may be supplied in suitable small bottles, small drums, 25 L drums, 200 L drums or other packaging formats depending on product properties and supplier confirmation.
Solid or low-melting products may require sealed bags, bottles, cartons, fiber drums with inner liners, moisture-protective packaging or other suitable packaging. Some products may require odor control, moisture protection, corrosion-resistant packaging, UN-approved packaging or specific transport labels depending on SDS and transport classification.
Sea, air, courier, LCL or FCL shipment options must be evaluated case by case. Some products may not be suitable for certain transport routes or small-volume courier shipment depending on dangerous goods classification, package size and destination requirements.
Common trade terms may include FOB China port, FCA warehouse, CFR/CIF destination port or DAP destination where applicable. Import clearance, local duties, taxes and destination compliance should be confirmed by the buyer or their appointed import agent.
Aromatic and Benzyl Amino Alcohols Available from Aure Chemical
Based on the above application segment, Shandong Aure Chemical can support sourcing and supply coordination for selected aromatic amino alcohols, benzyl amino alcohols and related substituted amino alcohol intermediates used in organic intermediate and specialty chemical synthesis.
Related products include N-phenyldiethanolamine, N-methyl-N-phenylethanolamine, N-benzylethanolamine, N,N-dibenzylethanolamine, N-benzyl-N-methylethanolamine, 3-benzylamino-1-propanol and 2-(4-fluorobenzylamino)ethanol.
For suitable products, Aure Chemical can help review product name, CAS number, target specification, quantity, packaging requirement, destination and required documentation. Available support may include quotation, specification confirmation, COA/SDS coordination, packaging review and export logistics discussion. Product availability, lead time, specification, packaging, documentation and shipment feasibility are subject to product and supplier confirmation.
Request Information or Quotation
To discuss aromatic or benzyl amino alcohol requirements, please provide the following information when sending an inquiry:
Product name and CAS number
Target purity, assay or specification
Required quantity for sample, trial order, batch order or annual consumption
Destination port or delivery address
Preferred trade term, such as FOB China port, FCA warehouse, CFR/CIF destination port or DAP destination where applicable
Preferred packaging or drum size
Required documents, such as COA, SDS, TDS, product overview or supplier questionnaire
Expected purchase schedule or project timeline
Any special impurity, color, water content, physical state or storage requirements
Contact Aure Chemical for Aromatic and Benzyl Amino Alcohols