1-(2-Ethoxy-ethyl)-2-piperidin-4-yl-1H-benzimidazole CAS 110963-63-8

Aure Chemical Delivers Reliable 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole (CAS 110963-63-8) at Consistent Quality

This benzimidazole derivative bearing an ethoxyethyl substituent and piperidine moiety supports advanced synthetic manipulations in regulated environments. Aure Chemical maintains material with specifications appropriate for pharmaceutical intermediate use and associated documentation.

Basic Information

CAS No.	110963-63-8
EC No.	Not available
Linear Formula	C16H23N3O
Molecular Weight	273.37
Appearance	Off-white to light brown solid
Melting Point	Not available (typical reference)
Boiling point	452 ± 40 °C (predicted, lit.)
Density	1.18 g/mL (predicted, lit.)
Solubility	Soluble in organic solvents including DMSO, methanol, and dichloromethane; limited solubility in water
Storage Conditions	Keep in a tightly closed container at 2-8°C, protected from light
Chemical Structure

Key Applications

• Pharmaceutical intermediate: Serves as a core building block in the synthesis of bilastine, a second-generation antihistamine active pharmaceutical ingredient, and an important component within Bilastine and specialty antihistamine intermediates for pharmaceutical development.

• API intermediate: Enables attachment of the ethoxyethyl group to the benzimidazole-piperidine framework essential for bilastine structure, making it relevant to piperazine and piperidine intermediates in API synthesis.

• Heterocyclic synthesis: Provides a functionalized benzimidazole scaffold for constructing complex nitrogen-heterocyclic systems in organic synthesis, especially among quinazolinone, benzimidazole and fused heterocycle intermediates.

• Medicinal chemistry research: Applied in the preparation of analogs and derivatives for antihistamine and related therapeutic explorations.

• Process development: Facilitates route evaluation and optimization for scalable production of high-purity pharmaceutical intermediates for API synthesis.

Aure Chemical: Your Reliable Partner

• Consistent product quality: Purity and key parameters controlled via standard analytical methods to provide dependable performance in synthetic workflows.

• Stable global supply: Robust supply arrangements ensure continuous availability from small research quantities to larger commercial needs.

• SDS and COA support: Comprehensive SDS and COA documentation prepared and provided to meet quality and regulatory expectations.

• Packaging and technical service: Packaging tailored in 1kg, 5kg, or 25kg options with suitable liners, supported by prompt technical discussions.