2-[4-(2-Chloroethyl)phenyl]-2-methylpropanoic acid CAS 2199440-16-7

Name: 2-[4-(2-Chloroethyl)phenyl]-2-methylpropanoic acid CAS 2199440-16-7
Brand: Aure Chemical
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Synonyms: 4-(2-Chloroethyl)-α,α-dimethylbenzeneacetic acid; Benzeneacetic acid, 4-(2-chloroethyl)-α,α-dimethyl-; Bilastine Impurity 40; Bilastine intermediate; 2-(4-(2-chloroethyl)phenyl)-2-methylpropionic acid; 2199440-16-7

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Product Details

Aure Chemical: Trusted Source of 2-[4-(2-Chloroethyl)phenyl]-2-methylpropanoic acid CAS 2199440-16-7

This chloroethyl-substituted propanoic acid derivative enables precise side-chain elaboration in multi-step pharmaceutical routes. Aure Chemical provides material with controlled specifications suited to intermediate requirements in regulated synthesis.

Basic Information

CAS No.	2199440-16-7
EC No.	Not available
Linear Formula	C12H15ClO2
Molecular Weight	226.70
Appearance	Off-white to pale yellow solid
Melting Point	Not available (typical reference)
Boiling point	353.6 ± 22.0 °C (predicted, lit.)
Density	1.162 ± 0.06 g/mL (predicted, lit.)
Solubility	Soluble in organic solvents such as methanol, dichloromethane, and ethyl acetate; limited solubility in water
Storage Conditions	Store in a tightly closed container at room temperature, protected from moisture and light
Chemical Structure

Key Applications

Pharmaceutical intermediate: A critical building block in the synthetic pathway to bilastine, supporting assembly of the antihistamine core structure and fitting naturally within Bilastine and specialty antihistamine intermediates.
API intermediate: Introduces the chloroethylphenyl propanoic acid fragment necessary for bilastine and analogous therapeutic molecules in advanced pharmaceutical synthesis.
Organic synthesis intermediate: Offers a reactive chloroethyl handle for nucleophilic substitutions on the gem-dimethyl propanoic scaffold used in pharmaceutical and fine chemical applications.
Laboratory research: Employed in exploratory routes and impurity profiling for antihistamine compound development, especially in the study of specialty antihistamine intermediates.
Process development: Aids in optimization of alkylation and coupling steps during scale-up of pharmaceutical intermediates and pharmaceutical intermediates for API synthesis.

Aure Chemical: Your Reliable Partner

Consistent product quality: Batch uniformity ensured through validated testing protocols to meet exacting standards for synthetic intermediate use.
Stable global supply: Dependable sourcing and shipment networks maintain availability for research, pilot, and production-scale demands internationally.
SDS and COA support: SDS, COA, and supporting analytical data furnished as required to facilitate quality control and regulatory compliance.
Packaging and technical service: Options such as 1kg, 5kg, or 25kg in fiber drums with PE liner, accompanied by responsive technical guidance.