GHS Classification: Flammable Liquid (GHS02), Exclamation Mark (GHS07)
Hazard Statements: Highly flammable liquid and vapor; may cause skin and eye irritation.
UN Number: UN 2924
Hazard Class: 3 (Flammable Liquids)
Packing Group: II
Tetramethyldisiloxane (TMDSO) CAS 3277-26-7
Discover Aure Chemical's Premium TMDSO Supply
Tetramethyldisiloxane (TMDSO) is a crucial organosilicon compound with the chemical formula (CH₃)₂HSi-O-SiH(CH₃)₂. It presents as a clear, colorless liquid, characterized by low viscosity, high volatility, and excellent chemical stability. The unique aspect of TMDSO lies in its molecular structure, which contains two active silicon-hydrogen (Si-H) bonds. This feature makes it a versatile chemical intermediate, demonstrating superior performance in a wide range of reactions.
Basic Information of Tetramethyldisiloxane
| CAS No.: | 3277-26-7 |
|---|---|
| EC No.: | 221-906-4 |
| Linear Formula: | (CH₃)₂HSi-O-SiH(CH₃)₂ |
| Molecular Weight: | 134.32 |
| Appearance: | Transparent Liquid |
| Melting Point: | <-78°C |
| Boiling point: | 70-71 °C (lit.) |
| Density: | 0.76 g/mL at 25 °C (lit.) |
| Solubility: | Soluble in Chloroform |
| Flash Point: | 14 °F |
| RIDADR: | UN 2924 3/PG 2 |
| Chemical Structure: | ![]() |
Applications of TMSO
Due to its distinctive chemical structure and reactivity, TMDSO plays a pivotal role in numerous industrial sectors and research applications:
Organosilicon Materials:
An essential monomer or cross-linking agent for hydrosilylation reactions, used in the synthesis of various organosilicon polymers, silicone rubbers, and silicone resins.
Utilized in the preparation of functional organosilicon materials with specialized properties.
Pharmaceutical and Agrochemical Intermediates:
Serves as an important silylating agent, used to protect or modify organic molecules containing hydroxyl, amino, and other functional groups.
Acts as a reducing agent or a reactant for specific reactions in drug synthesis.
Fine Chemicals:
Employed as a coupling agent to enhance interfacial adhesion between inorganic fillers and organic polymers.
Used as a selective reducing agent in certain organic synthesis reactions.
Can function as a diluent or solvent for specific systems.
Analytical Applications:
Can be used as a gas chromatography (GC) stationary phase for the separation and analysis of organic compounds.
Used as a reference substance or a solvent component in Nuclear Magnetic Resonance (NMR) spectroscopy.
Surface Treatment:
Applied for the hydrophobization of material surfaces, improving their water repellency.
Why Choose Aure Chemical's TMDSO?
Opting for Aure Chemical as your Tetramethyldisiloxane supplier means choosing:
Exceptional Quality: We commit to providing high-purity TMDSO, ensuring consistency and success in your experiments and production processes.
Rigorous Quality Control: Our products undergo strict quality checks to meet and exceed industry standards.
Reliable Supply: Consistent production capabilities and inventory ensure timely delivery, supporting your production schedules.
Expert Technical Support: Our professional team is readily available to provide product information and technical consultation.
Hazards Classification


Packaging, Logistics & Compliance Capabilities
Aure Chemical provides flexible packaging solutions, compliant logistics arrangements, and controlled storage practices to support laboratory-scale, pilot-scale, and commercial-scale global supply.
Packaging Options
- 25 kg / 50 kg bags (fiber drum, aluminum bag, HDPE drum)
- 100 kg / 200 kg steel or HDPE drums
- 500 kg / 1000 kg IBC containers
- Bulk liquids in ISO tank containers
- Customized packaging upon request
Transportation Modes
- Sea freight (FCL / LCL)
- Air freight for selected products
- Road and rail transportation
- Dangerous & non-dangerous cargo handling
- Incoterms: EXW, FOB, CFR, CIF, DAP, DDP
Storage & Handling
- Dry, cool, and well-ventilated warehouses
- Segregation by hazard class
- FIFO inventory management
- Temperature-controlled storage if required
- Regular inspection & labeling control
Documentation & Compliance
- Safety Data Sheet (SDS)
- Certificate of Analysis (COA)
- Dangerous Goods Declaration (DGD)
- Packing List & Commercial Invoice
- IMDG / IATA / ADR compliant labeling
For packaging customization or logistics consultation, please contact us.


