Aure Chemical: Your Trusted Source for High-Purity Triflic Anhydride (CAS 358-23-6)
Aure Chemical is a premier global supplier of high-quality Triflic Anhydride, formally known as Trifluoromethanesulfonic Anhydride. Identified by its CAS number 358-23-6, Triflic Anhydride is a colorless, fuming liquid renowned for its exceptional reactivity and powerful electrophilic character. It is one of the most potent triflating agents available, widely used for converting hydroxyl groups into excellent leaving groups (triflates), thereby facilitating numerous synthetic transformations. This versatile compound is indispensable as a strong electrophile and dehydrating agent in complex organic synthesis, and serves as a highly effective catalyst for various reactions in pharmaceutical, agrochemical, and advanced material science applications. Aure Chemical is committed to providing Triflic Anhydride that meets stringent purity and performance requirements, ensuring consistent and reliable results for your most demanding industrial and research applications. Partner with us for a dependable supply of this critical chemical.
Product Overview & Key Properties
Triflic Anhydride (CAS No. 358-23-6) is meticulously produced and rigorously tested to meet stringent quality standards. We offer various grades to suit your specific application requirements:
| CAS No.: | 358-23-6 |
| EC No.: | 206-616-8 |
| Linear Formula: | (CF₃SO₂)₂O |
| Molecular Weight: | 282.14 |
| Appearance: | Colorless, fuming liquid. |
| Melting Point: | -80°C |
| Boiling point: | 81-83 °C (lit.) |
| Density: | 1.677 g/mL at 25 °C (lit.) |
| Reactivity: | Highly reactive with nucleophiles, water, and protic solvents. |
| Purity: | Available in high purity grades (e.g., 99% min) for sensitive synthetic and catalytic applications. |
| RIDADR: | UN 3265 8/PG 2 |
| Chemical Structure: |  |
Our commitment to delivering high-purity Triflic Anhydride ensures a reliable and efficient component for your critical processes, offering consistent quality for diverse synthetic and industrial applications.
Primary Applications of Triflic Anhydride (Trifluoromethanesulfonic Anhydride)
Triflic Anhydride's extreme electrophilicity and potent triflating ability make it an invaluable reagent with significant applications in various advanced chemical processes:
Derivatizing Agent / Triflating Agent:
Triflic Anhydride is primarily used to introduce the trifluoromethanesulfonyl (triflyl) group ($CF_3SO_2-$) into organic molecules. This is crucial for:
Converting Hydroxyl Groups: Efficiently transforms alcohols into highly reactive triflates, excellent leaving groups for nucleophilic substitution reactions (e.g., in stereoselective syntheses).
Activating Carboxylic Acids: Forms mixed anhydrides that are powerful acylating agents.
Preparing Triflates: Synthesizing various triflate esters and salts, which are themselves versatile reagents and catalysts.
Strong Electrophile in Organic Synthesis:
It acts as a potent electrophile in Friedel-Crafts type reactions, Vilsmeier-Haack reactions, and other electrophilic aromatic substitutions, allowing for precise and effective functionalization of organic compounds.
Dehydrating Agent:
Its strong affinity for water makes it an effective dehydrating agent in certain sensitive organic reactions, particularly when forming unsaturated compounds or anhydrides.
Catalyst in Chemical Transformations:
Triflic Anhydride serves as a powerful catalyst for various reactions, including:
Polymerization: Initiates or catalyzes the polymerization of a range of monomers, leading to specialty polymers.
Cyclization Reactions: Promotes the formation of cyclic compounds.
Rearrangements: Facilitates complex molecular rearrangements.
Pharmaceutical and Agrochemical Development:
It is a critical reagent in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, enabling challenging bond formations and stereoselective transformations.
Why Choose Aure Chemical for Your Triflic Anhydride Supply?
Aure Chemical is dedicated to providing superior chemical solutions and unparalleled customer support. By partnering with us for your Triflic Anhydride requirements, you benefit from:
Exceptional Purity & Consistent Quality: Our Triflic Anhydride is manufactured to stringent purity specifications, crucial for achieving optimal and reproducible results in sensitive organic syntheses and demanding industrial processes.
Reliable Global Supply Chain: We maintain a robust and efficient global supply network, guaranteeing timely and secure delivery of this essential, highly reactive chemical to your facilities worldwide, with specialized packaging and handling expertise.
Expert Technical Support: Our dedicated team of specialists is readily available to offer comprehensive guidance on product application, safe handling procedures, optimal storage, and usage in your specific chemical processes, ensuring maximum safety and efficiency when working with this potent reagent.
Commitment to Quality & Responsible Stewardship: We adhere to the highest industry standards for quality management, environmental responsibility, and product stewardship across all our operations, ensuring peace of mind for our clients and sustainable sourcing practices.
Customized Solutions: We understand that different applications may require specific purity levels. We are open to discussing customized solutions to meet your exact requirements.
Choose Aure Chemical for a trustworthy and dependable supply of high-quality Triflic Anhydride. We're ready to empower your most advanced chemical synthesis and research endeavors with an unwavering commitment to quality and excellence.
Packaging, Transportation & Storage Solutions
At Aure Chemical, we understand the critical importance of rigorous packaging, transportation, and storage for chemical products. To ensure the safety and integrity of the products you purchase, and to comply with international and national regulations, we provide the following general guidelines. Please note that each specific product has its own Safety Data Sheet (SDS), which contains the most detailed and authoritative information on packaging, transportation, and storage. We strongly advise you to consult and strictly adhere to the SDS for the respective product.
| I. Packaging Solutions | II. Transportation Solutions | III. Storage Solutions |
We utilize various UN (United Nations) certified packaging containers based on the chemical nature, hazard class, and transportation requirements of our products. Common packaging types include, but are not limited to: Steel Drums: Suitable for a wide range of liquid and solid products, especially flammable liquids. Plastic Drums/Jerricans: Primarily used for corrosive liquids like acids and bases, or substances incompatible with metal. Composite Drums: Combine the corrosion resistance of a plastic inner liner with the strength of a steel or fiber outer shell. IBCs (Intermediate Bulk Containers): Often referred to as "Tote Bins" or "Cubic Tanks," these are used for larger volumes of liquid or solid dangerous goods, offering efficient storage and transport solutions. Lined Bags or Fibre Drums: Primarily used for powdered or granular solids. Glass Bottles: Typically used as inner packaging for small quantities of high-purity or specialized chemicals, requiring additional absorbent material and sturdy outer packaging (e.g., wooden crates, fiberboard boxes). Steel Cylinders: Specifically designed and constructed as pressure vessels for the storage and transport of compressed, liquefied, or dissolved gases. Available in various capacities and pressure ratings, they are built to withstand high internal pressures and ensure the safe containment of gaseous substances.
All packaging undergoes stringent testing and complies with UN packaging performance levels to ensure product safety under normal transport conditions. | We strictly adhere to international and regional regulations for the transport of dangerous goods, ensuring full compliance and safety from our facility to your delivery point. Sea Freight (IMDG Code): We strictly comply with the International Maritime Dangerous Goods (IMDG) Code, using UN-certified containers and ensuring proper dangerous goods declaration, marking, and stowage. Air Freight (IATA DGR): We follow the International Air Transport Association (IATA) Dangerous Goods Regulations, which impose the strictest requirements for packaging, labeling, documentation, and quantity limitations. Road/Rail Transport (ADR/RID & Local Regulations): We comply with the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR), the Regulations concerning the International Carriage of Dangerous Goods by Rail (RID), and specific national/regional regulations to ensure safe land transport.
Regardless of the transport mode, we will provide the following essential documentation: Safety Data Sheet (SDS/MSDS): Provides product hazard information, safe handling guidelines, emergency measures, etc. Dangerous Goods Declaration (DGD): Detailed information on dangerous goods, packing group, UN number, etc., for carriers and relevant authorities. Other Necessary Certifications or Documents: Such as Certificates of Analysis (COA).
Upon receiving your shipment, please carefully verify the integrity of the packaging and the label information.
| Proper storage is crucial for maintaining product quality and ensuring operational safety. The following are general storage principles: Dedicated Areas: Dangerous chemicals should be stored in designated warehouses or areas that meet safety standards, away from residential zones and densely populated areas. Segregated Storage: Strictly classify and segregate products according to their hazard class to prevent incompatible substances from being stored together and causing dangerous reactions (e.g., acids and bases separated, flammables away from oxidizers). Good Ventilation: Storage areas should maintain good natural or forced ventilation to prevent the accumulation of hazardous gases or vapors. Temperature & Humidity Control: Control the temperature and humidity of the storage environment according to the recommendations in the SDS. Avoid direct sunlight and extreme temperatures. Fire and Explosion Prevention: Storage areas for flammable and explosive products should be equipped with adequate fire-fighting equipment, prohibit open flames, and ensure electrical equipment meets explosion-proof standards. Clear Labeling: All storage containers and areas should have clear, conspicuous hazard labels and warning signs. Spill Response: Storage areas should be equipped with appropriate spill response equipment and materials, and personnel should be familiar with emergency procedures. Regular Inspections: Periodically inspect the integrity of storage containers to ensure no leaks or damage, and verify label information. Away from Food and Drinking Water: Avoid cross-contamination.
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| Should you have any questions regarding the packaging, transportation, or storage of specific products, or require a customized solution, please do not hesitate to contact us. |
