Discover Aure Chemical's Premium Trifluoroacetic Acid (CAS 76-05-1) Supply
Aure Chemical is a leading global supplier of Trifluoroacetic Acid (TFA), also known as 2,2,2-Trifluoroethanoic acid. This highly versatile and exceptionally strong organic acid is a cornerstone in advanced chemistry, prized for its unique combination of strong acidity, excellent solvent properties, and high volatility. TFA is an indispensable reagent, catalyst, and solvent across a broad spectrum of high-tech industries and research applications.
Product Overview & Key Properties
Trifluoroacetic Acid (CAS No. 76-05-1) is manufactured to the highest purity standards, ensuring optimal performance and reliability for your most demanding applications:
| CAS No.: | 76-05-1 |
| EC No.: | 200-929-3 |
| Linear Formula: | CF₃COOH |
| Molecular Weight: | 114.02 |
| Appearance: | Transparent Liquid |
| Odor: | Pungent, sharp, vinegar-like odor |
| Melting Point: | -15.2 °C |
| Boiling point | 72 °C |
| Density: | 1.489 g/mL at 25 °C |
| Solubility: | Miscible with water and most organic solvents. |
| Nature: | Extremely corrosive, highly volatile, strong acid (stronger than sulfuric acid), non-oxidizing. |
| RIDADR: | UN 2699 8/PG 1 |
| Chemical Structure: |  |
Our commitment to delivering high-purity TFA ensures consistent and superior results for your specialized synthesis and analytical needs.
Primary Applications of Trifluoroacetic Acid (TFA)
Trifluoroacetic Acid's unique chemical profile, characterized by its strong acidity and the electron-withdrawing effects of its fluorine atoms, drives its extensive utility:
Peptide Synthesis & Protein Chemistry:
TFA is absolutely critical in solid-phase peptide synthesis (SPPS), where it's used to deprotect N-terminal Boc (tert-butyloxycarbonyl) groups. Its high volatility allows for easy removal after reaction, making it ideal for the sequential synthesis of peptides and proteins.
Pharmaceutical & Agrochemical Manufacturing:
As a powerful catalyst and solvent, TFA plays a vital role in the synthesis of various active pharmaceutical ingredients (APIs) and agrochemicals. It's used in numerous reactions requiring strong acidic conditions, such as esterifications, alkylations, and acylations.
Chromatography & Analytical Chemistry:
TFA is a common mobile phase modifier in High-Performance Liquid Chromatography (HPLC), particularly for separating peptides, proteins, and other polar compounds. Its volatility ensures it won't interfere with subsequent mass spectrometry analysis, making it an ideal ion-pairing reagent.
Polymer Science & Advanced Materials:
Used as a solvent for dissolving various polymers (e.g., polyamides, polyesters) that are otherwise insoluble in common organic solvents. It also serves as a reagent in the synthesis of specialized fluoropolymers and other advanced materials.
General Organic Synthesis:
Beyond its specific applications, TFA acts as a versatile strong acid catalyst, solvent, and reagent for numerous organic reactions, including Friedel-Crafts acylations, deprotections, and oxidation reactions.
Why Choose Aure Chemical for Your Trifluoroacetic Acid (TFA) Supply?
Aure Chemical is dedicated to providing superior chemical solutions and unparalleled customer support. By partnering with us for your Trifluoroacetic Acid requirements, you benefit from:
Exceptional Purity: Our TFA is manufactured to the highest purity specifications, crucial for sensitive applications like peptide synthesis and analytical chromatography.
Reliable Global Supply: We maintain a robust and efficient supply chain, guaranteeing timely and secure delivery of this specialized chemical to your facilities worldwide.
Expert Technical Support: Our team of experienced chemists and specialists is readily available to offer comprehensive guidance on product application, safe handling, and storage of TFA.
Commitment to Quality & Safety: We adhere to the highest industry standards for quality management, safety, and environmental responsibility across all our operations.
Choose Aure Chemical for a trustworthy and dependable supply of high-quality Trifluoroacetic Acid. We are ready to support your most complex and innovative chemical endeavors.
Packaging, Transportation & Storage Solutions
At Aure Chemical, we understand the critical importance of rigorous packaging, transportation, and storage for chemical products. To ensure the safety and integrity of the products you purchase, and to comply with international and national regulations, we provide the following general guidelines. Please note that each specific product has its own Safety Data Sheet (SDS), which contains the most detailed and authoritative information on packaging, transportation, and storage. We strongly advise you to consult and strictly adhere to the SDS for the respective product.
| I. Packaging Solutions | II. Transportation Solutions | III. Storage Solutions |
We utilize various UN (United Nations) certified packaging containers based on the chemical nature, hazard class, and transportation requirements of our products. Common packaging types include, but are not limited to: Steel Drums: Suitable for a wide range of liquid and solid products, especially flammable liquids. Plastic Drums/Jerricans: Primarily used for corrosive liquids like acids and bases, or substances incompatible with metal. Composite Drums: Combine the corrosion resistance of a plastic inner liner with the strength of a steel or fiber outer shell. IBCs (Intermediate Bulk Containers): Often referred to as "Tote Bins" or "Cubic Tanks," these are used for larger volumes of liquid or solid dangerous goods, offering efficient storage and transport solutions. Lined Bags or Fibre Drums: Primarily used for powdered or granular solids. Glass Bottles: Typically used as inner packaging for small quantities of high-purity or specialized chemicals, requiring additional absorbent material and sturdy outer packaging (e.g., wooden crates, fiberboard boxes). Steel Cylinders: Specifically designed and constructed as pressure vessels for the storage and transport of compressed, liquefied, or dissolved gases. Available in various capacities and pressure ratings, they are built to withstand high internal pressures and ensure the safe containment of gaseous substances.
All packaging undergoes stringent testing and complies with UN packaging performance levels to ensure product safety under normal transport conditions. | We strictly adhere to international and regional regulations for the transport of dangerous goods, ensuring full compliance and safety from our facility to your delivery point. Sea Freight (IMDG Code): We strictly comply with the International Maritime Dangerous Goods (IMDG) Code, using UN-certified containers and ensuring proper dangerous goods declaration, marking, and stowage. Air Freight (IATA DGR): We follow the International Air Transport Association (IATA) Dangerous Goods Regulations, which impose the strictest requirements for packaging, labeling, documentation, and quantity limitations. Road/Rail Transport (ADR/RID & Local Regulations): We comply with the European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR), the Regulations concerning the International Carriage of Dangerous Goods by Rail (RID), and specific national/regional regulations to ensure safe land transport.
Regardless of the transport mode, we will provide the following essential documentation: Safety Data Sheet (SDS/MSDS): Provides product hazard information, safe handling guidelines, emergency measures, etc. Dangerous Goods Declaration (DGD): Detailed information on dangerous goods, packing group, UN number, etc., for carriers and relevant authorities. Other Necessary Certifications or Documents: Such as Certificates of Analysis (COA).
Upon receiving your shipment, please carefully verify the integrity of the packaging and the label information.
| Proper storage is crucial for maintaining product quality and ensuring operational safety. The following are general storage principles: Dedicated Areas: Dangerous chemicals should be stored in designated warehouses or areas that meet safety standards, away from residential zones and densely populated areas. Segregated Storage: Strictly classify and segregate products according to their hazard class to prevent incompatible substances from being stored together and causing dangerous reactions (e.g., acids and bases separated, flammables away from oxidizers). Good Ventilation: Storage areas should maintain good natural or forced ventilation to prevent the accumulation of hazardous gases or vapors. Temperature & Humidity Control: Control the temperature and humidity of the storage environment according to the recommendations in the SDS. Avoid direct sunlight and extreme temperatures. Fire and Explosion Prevention: Storage areas for flammable and explosive products should be equipped with adequate fire-fighting equipment, prohibit open flames, and ensure electrical equipment meets explosion-proof standards. Clear Labeling: All storage containers and areas should have clear, conspicuous hazard labels and warning signs. Spill Response: Storage areas should be equipped with appropriate spill response equipment and materials, and personnel should be familiar with emergency procedures. Regular Inspections: Periodically inspect the integrity of storage containers to ensure no leaks or damage, and verify label information. Away from Food and Drinking Water: Avoid cross-contamination.
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| Should you have any questions regarding the packaging, transportation, or storage of specific products, or require a customized solution, please do not hesitate to contact us. |
